A prospective study of mandibular trabecular bone to predict fracture incidence in women: a low-cost screening tool in the dental clinic.
نویسندگان
چکیده
Bone structure is the key to the understanding of fracture risk. The hypothesis tested in this prospective study is that dense mandibular trabeculation predicts low fracture risk, whereas sparse trabeculation is predictive of high fracture risk. Out of 731 women from the Prospective Population Study of Women in Gothenburg with dental examinations at baseline 1968, 222 had their first fracture in the follow-up period until 2006. Mandibular trabeculation was defined as dense, mixed dense plus sparse, and sparse based on panoramic radiographs from 1968 and/or 1980. Time to fracture was ascertained and used as the dependent variable in three Cox proportional hazards regression analyses. The first analysis covered 12 years of follow-up with self-reported endpoints; the second covered 26 years of follow-up with hospital verified endpoints; and the third combined the two follow-up periods, totaling 38 years. Mandibular trabeculation was the main independent variable predicting incident fractures, with age, physical activity, alcohol consumption and body mass index as covariates. The Kaplan-Meier curve indicated a graded association between trabecular density and fracture risk. During the whole period covered, the hazard ratio of future fracture for sparse trabeculation compared to mixed trabeculation was 2.9 (95% CI: 2.2-3.8, p<0.0001), and for dense versus mixed trabeculation was 0.21 (95% CI: 0.1-0.4, p<0.0001). The trabecular pattern was a highly significant predictor of future fracture risk. Our findings imply that dentists, using ordinary dental radiographs, can identify women at high risk for future fractures at 38-54 years of age, often long before the first fracture occurs.
منابع مشابه
Mandibular Trabecular Bone Analysis Using Local Binary Pattern for Osteoporosis Diagnosis
Background: Osteoporosis is a systemic skeletal disease characterized by low bone mineral density (BMD) and micro-architectural deterioration of bone tissue, leading to bone fragility and increased fracture risk. Since Panoramic image is a feasible and relatively routine imaging technique in dentistry; it could provide an opportunistic chance for screening osteoporosis. In this regard, numerous...
متن کاملبرسی شاخصهای رادیوفورمومترریک
Statement of Problem: Bone material density (BMD) is significantly decreased among postmenopausal women leading to the most common metabolic disease, osteoporosis.Multiple bone fractures are of the most important consequences of this disease, which cost too much for thesociety. One of the cheapest and most available methods for the diagnosis of bone density changes is bone radiomorphometric eva...
متن کاملThe Role of Lingual Bone Grafting in the Treatment of Displaced Edentulous Mandibular Fracture with Severe Atrophy
Introduction: Treatment of edentulous atrophic mandible with severe atrophy is a challenge based on local conditions and systemic diseases confronted by the age group affected. If bone grafting is indicated, it is often used in lateral or inferior aspects of the mandible. Case Report: A 70-year-old male with a unilateral fracture of the atrophied left mandibular body was managed by lingual bon...
متن کاملPrevalence of Temporomandibular Disorders and its Relationship with Demographic Variables, Previous Orthodontic Treatment, and Mandibular Mobility in Patients Attending Sari Dental School Clinic
Background and purpose: The present study assessed the incidence of Temporomandibular Disorders (TMD) and its relationship with demographic variables, previous orthodontic treatment, and mandibular mobility in patients attending Sari Dental School. Materials and methods: In this cross-sectional study, 68 individuals were randomly selected. Data were obtained by interviewing the patients and cl...
متن کاملCorrelation of Bone Mineral Density and Fractal Analysis of the Mandibular Condyle in Women with Temporomandibular Joint Osteoarthritis: A Pilot Study
Background and Aim: Temporomandibular joint osteoarthritis (TMJOA) appears to be more common in osteoporotic patients. Fractal analysis is a mathematical method that can be used to assess trabecular bone. The aim of this study was to assess the correlation of bone mineral density (BMD) and fractal dimension (FD) of the condyles in women with TMJOA using cone-beam computed tomography (CBCT). ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Bone
دوره 49 4 شماره
صفحات -
تاریخ انتشار 2011